org.drugis.addis.presentation.TreatmentDefinitionsGraphModel.java Source code

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Here is the source code for org.drugis.addis.presentation.TreatmentDefinitionsGraphModel.java

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/*
 * This file is part of ADDIS (Aggregate Data Drug Information System).
 * ADDIS is distributed from http://drugis.org/.
 * Copyright  2009 Gert van Valkenhoef, Tommi Tervonen.
 * Copyright  2010 Gert van Valkenhoef, Tommi Tervonen, Tijs Zwinkels,
 * Maarten Jacobs, Hanno Koeslag, Florin Schimbinschi, Ahmad Kamal, Daniel
 * Reid.
 * Copyright  2011 Gert van Valkenhoef, Ahmad Kamal, Daniel Reid, Florin
 * Schimbinschi.
 * Copyright  2012 Gert van Valkenhoef, Daniel Reid, Jol Kuiper, Wouter
 * Reckman.
 * Copyright  2013 Gert van Valkenhoef, Jol Kuiper.
 *
 * This program is free software: you can redistribute it and/or modify
 * it under the terms of the GNU General Public License as published by
 * the Free Software Foundation, either version 3 of the License, or
 * (at your option) any later version.
 *
 * This program is distributed in the hope that it will be useful,
 * but WITHOUT ANY WARRANTY; without even the implied warranty of
 * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
 * GNU General Public License for more details.
 *
 * You should have received a copy of the GNU General Public License
 * along with this program.  If not, see <http://www.gnu.org/licenses/>.
 */

package org.drugis.addis.presentation;

import java.util.ArrayList;
import java.util.Collection;
import java.util.HashMap;
import java.util.HashSet;
import java.util.Map;
import java.util.Set;

import javax.swing.event.ListDataEvent;
import javax.swing.event.ListDataListener;

import org.apache.commons.collections15.CollectionUtils;
import org.drugis.addis.entities.Arm;
import org.drugis.addis.entities.OutcomeMeasure;
import org.drugis.addis.entities.Study;
import org.drugis.addis.entities.treatment.TreatmentDefinition;
import org.jgrapht.graph.ListenableUndirectedGraph;

import com.jgoodies.binding.list.ObservableList;

public class TreatmentDefinitionsGraphModel extends
        ListenableUndirectedGraph<TreatmentDefinitionsGraphModel.Vertex, TreatmentDefinitionsGraphModel.Edge> {
    private static final long serialVersionUID = -7829573824453914937L;

    public static class Vertex {
        private TreatmentDefinition d_definition;
        private int d_sampleSize;

        public Vertex(TreatmentDefinition def, int size) {
            d_definition = def;
            d_sampleSize = size;
        }

        public TreatmentDefinition getTreatmentDefinition() {
            return d_definition;
        }

        public int getSampleSize() {
            return d_sampleSize;
        }

        @Override
        public String toString() {
            return d_definition.getLabel();
        }
    }

    public static class Edge {
        private int d_studies;

        public Edge(int studies) {
            d_studies = studies;
        }

        public int getStudyCount() {
            return d_studies;
        }

        public void setStudyCount(int studies) {
            d_studies = studies;
        }

        @Override
        public String toString() {
            return Integer.toString(d_studies);
        }
    }

    protected ObservableList<TreatmentDefinition> d_definitions;
    private ObservableList<Study> d_studies;
    protected boolean d_rebuildNeeded;
    private final ValueHolder<OutcomeMeasure> d_om;
    private Map<TreatmentDefinition, Set<Study>> d_studiesMeasuringDefinition;

    public TreatmentDefinitionsGraphModel(ObservableList<Study> studies,
            ObservableList<TreatmentDefinition> definitions, ValueHolder<OutcomeMeasure> om) {
        super(Edge.class);

        d_definitions = definitions;
        d_studies = studies;
        d_om = om;

        ListDataListener rebuildNeededListener = new ListDataListener() {
            public void intervalRemoved(ListDataEvent e) {
                d_rebuildNeeded = true;
            }

            public void intervalAdded(ListDataEvent e) {
                d_rebuildNeeded = true;
            }

            public void contentsChanged(ListDataEvent e) {
                d_rebuildNeeded = true;
            }
        };

        d_rebuildNeeded = true;
        d_studies.addListDataListener(rebuildNeededListener);
        d_definitions.addListDataListener(rebuildNeededListener);

        rebuildGraph();
    }

    public void rebuildGraph() {
        if (!d_rebuildNeeded) {
            return;
        }

        initStudiesMeasuringDefinition();

        // Add vertices
        ArrayList<Vertex> verts = new ArrayList<Vertex>(vertexSet());
        removeAllVertices(verts);
        for (TreatmentDefinition d : d_definitions) {
            addVertex(new Vertex(d, calculateSampleSize(d)));
        }

        // Add edges
        ArrayList<Edge> edges = new ArrayList<Edge>(edgeSet());
        removeAllEdges(edges);
        for (int i = 0; i < (d_definitions.size() - 1); ++i) {
            for (int j = i + 1; j < d_definitions.size(); ++j) {
                Collection<Study> studies = getStudies(d_definitions.get(i), d_definitions.get(j));
                if (studies.size() > 0) {
                    addEdge(findVertex(d_definitions.get(i)), findVertex(d_definitions.get(j)),
                            new Edge(studies.size()));
                }
            }
        }

        d_rebuildNeeded = false;
    }

    private void initStudiesMeasuringDefinition() {
        d_studiesMeasuringDefinition = new HashMap<TreatmentDefinition, Set<Study>>();
        for (TreatmentDefinition d : d_definitions) {
            d_studiesMeasuringDefinition.put(d, new HashSet<Study>());
            for (Study s : d_studies) {
                for (Arm arm : s.getArms()) {
                    if (d.match(s, arm) && s.getOutcomeMeasures().contains(d_om.getValue())) {
                        d_studiesMeasuringDefinition.get(d).add(s);
                    }
                }
            }
        }
    }

    public Vertex findVertex(TreatmentDefinition definition) {
        for (Vertex v : vertexSet()) {
            if (v.getTreatmentDefinition().equals(definition)) {
                return v;
            }
        }
        return null;
    }

    private int calculateSampleSize(TreatmentDefinition d) {
        int n = 0;
        for (Study s : getStudies(d)) {
            n += s.getSampleSize();
        }
        return n;
    }

    /**
     * Return the list of drugs that are included in at least one of the studies having the correct indication
     * and outcome.
     */
    public ObservableList<TreatmentDefinition> getDefinitions() {
        return d_definitions;
    }

    /**
     * Return the studies with the correct indication and outcome that compare the given drugs.
     */
    public Collection<Study> getStudies(TreatmentDefinition a, TreatmentDefinition b) {
        return CollectionUtils.intersection(getStudies(a), getStudies(b));
    }

    /**
     * Return the studies with the correct indication and outcome that include the given drug.
     */
    public Collection<Study> getStudies(TreatmentDefinition d) {
        return d_studiesMeasuringDefinition.get(d);
    }
}