You can use regular string operations on CLOBs:
The following code implements a search or indexing routine for all large text files loaded in the database.
declare
v_manual_cl CLOB;
v_nr NUMBER;
v_tx VARCHAR2 (2000);
v_add_tx VARCHAR2 (2000):='Loaded: '||TO_CHAR(SYSDATE,'mm/dd/yyyy hh24:mi');
begin
select manual_cl
into v_manual_cl
from t_product
where id = 1
for update;
DBMS_LOB.writeappend (v_manual_cl,LENGTH (v_add_tx), v_add_tx);
v_nr := INSTR (v_manual_cl, 'Loaded:', -1);
v_tx := SUBSTR (v_manual_cl, v_nr);
DBMS_OUTPUT.put_line (v_tx);
end;